A. F. Parlow Library

Los Angeles County Harbor-UCLA Medical Center
A.F. Parlow Library of Health Sciences

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Los Angeles Biomedical Research Institute
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Evidence-Based Medicine Resources

Definition:

Evidence based medicine is the conscientious, explicit, and judicious use of current best evidence in making decisions about the care of individual patients. The practice of evidence based medicine means integrating individual clinical expertise with the best available external clinical evidence from systematic research.
Sackett DL, Rosenberg WMC, Gray JAM, Haynes RB, Richardson WS. Evidence based medicine: what it is and what it isn't. BMJ 1996; 312: 71-2.

Read the full-text article here:
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2349778

Five Steps of Evidence-Based Practice:

What is EBM? - Centre for Evidence-Based Medicine:
http://www.cebm.net/index.aspx?o=1914

1. Asking Focused Questions: translation of uncertainty to an answerable question

2. Finding the Evidence: systematic retrieval of the best evidence available

3. Critical Appraisal: testing evidence for validity, clinical relevance, and applicability

4. Making a Decision: application of results in practice

5. Evaluating Performance: auditing evidence-based decisions

Introductory Material and Assessing the Literature:

The following resources contain additional information about evidence-based medicine. They also provide tools for clinical evidence assessment and decision-making.

Critical Appraisal Worksheets - Centre for Evidence-Based Medicine:
http://www.cebm.utoronto.ca/teach/materials/caworksheets.htm

Evidence-Based Dermatology - Bigby, Corona, & Szklo:
http://www.accessmedicine.com.journals.labiomed.org/content.aspx?aid=2965154

Evidence-Based Endocrinology & Clinical Epidemiology - Aron:
http://www.accessmedicine.com.journals.labiomed.org/content.aspx?aid=2628319

Evidence-Based Medicine - Mark:
http://www.accessmedicine.com.journals.labiomed.org/content.aspx?aID=2858296

Evidence Based Medicine Toolkit - University of Alberta:
http://www.ebm.med.ualberta.ca/

Introduction to Evidence-Based Medicine - UNC Chapel Hill and Duke:
http://www.hsl.unc.edu/services/tutorials/ebm/index.htm

Methods of Evidence-Based Medicine and Decision Analysis - Dawson & Trapp:
http://www.accessmedicine.com.journals.labiomed.org/content.aspx?aid=2048860

Users' Guides to Evidence-Based Practice - Center for Health Evidence:
http://www.cche.net.usersguides.main.asp

Evidence-Based Resources:

The following evidence-based resources assist you in retrieving the clinical evidence you need.

ACP PIER & AHFS DI® Essentials™ - American College of Physicians:
https://journals.labiomed.org/login?url=http://online.statref.com//Default.aspx?grpalias=SCELCm

Bandolier Knowledge:
http://www.medicine.ox.ac.uk/bandolier/knowledge.html

Cochrane Database of Systematic Reviews: (Must be onsite for access)
http://www.interscience.wiley.com/cochrane/

Health Services/Technology Assessment Text (HSTAT) - National Library of Medicine:
http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=hstat

National Guideline Clearinghouse:
http://www.guidelines.gov/

PubMed Clinical Queries:
http://www.ncbi.nlm.nih.gov/entrez/query/static/clinical.shtml

TRIP Database:
http://www.tripdatabase.com/index.html

U.S. Preventive Services Task Force - Agency for Healthcare Research and Quality:
http://www.ahrq.gov/clinic/uspstfix.htm